Combination of Montelukast Sodium and Fexofenadine HCL: A Comprehensive Overview of Efficacy and Safety in Allergy and Asthma Management

H. Patel, Vasav and K. Patel, Khushbu and Patel, C. N. (2025) Combination of Montelukast Sodium and Fexofenadine HCL: A Comprehensive Overview of Efficacy and Safety in Allergy and Asthma Management. International Journal of Innovative Science and Research Technology, 10 (4): 25apr1253. pp. 4502-4504. ISSN 2456-2165

Abstract

Allergic conditions and asthma significantly impact the quality of life and require effective managementstrategies. Montelukast sodium, a leukotriene receptor antagonist, and Fexofenadine HCL, a second-generation antihistamine, are widely used in allergy and asthma treatment. Their combination offers a dual mechanism of action that targets both histamine and leukotriene-mediated pathways, providing enhanced symptom relief. This review explores the pharmacological properties, clinical efficacy, safety profile, and potential benefits of this combination therapy. It highlights its role in improving respiratory function and controlling allergic reactions with minimal adverse effects.

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